Lazio vs Roma: Tips, Odds, and Match Preview
Lazio and Roma will lock horns for the 163rd time in Serie A history this Sunday, and it will be a match where both teams will fight for more than just three points.

Pride, bragging rights and honour will be at stake in this matchup, although based on recent form, Roma seem to be in better shape ahead of this contest.
Can Lazio Turn Things Around Under Maurizio Sarri’s Lead?
Lazio are a few echelons below the Serie A title contenders, and they’re not expected to fight for the 2025/26 Scudetto. Fighting for a potential UEFA Champions League berth would be considered a massive success, but it’s hard to see them putting on a successful challenge for a Top 4 spot given how poor their campaign has been to date.
Lazio have lost two of their first three league matches, and their 1-0 away loss at Sassuolo was their worst outing of the campaign to date. In danger of losing three of their first four Serie A matches for the first time in 50 years, Lazio have also won just one of their previous six league matches dating back to the latter stages of the 2024-25 season (W1, D2, L3). At least they can boast of their solid record at home, where they’ve lost just once in their last nine league contests (W2, D6, L1).
Lazio Injury & Suspension News
Lazio will be without Manuel Lazzari (calf), Patric (ankle) and Matias Vecino (thigh). Nicolo Rovella is doubtful due to an undisclosed injury, but chances are he won’t be available as well.
Roma’s Binary Campaign Yielding Positive Results
Even though “binary” might not be a term commonly used in soccer, that’s the best way to describe Roma’s campaign so far. The Giallorossi have seen each of their first three 2025-26 Serie A matches ending with an identical 1-0 result, although they’ve managed to come out on top often (W2, L1). Still, they need to bounce back after losing to Torino in the previous round.
Despite dominating the possession and creating the best chances throughout the game, Roma were simply unable to penetrate Torino’s stout defensive line. The lack of creativity shouldn’t be an issue on a team where Paulo Dybala stars, but it’s clear that Roma need to make some improvements in the final third. This match against Lazio is expected to be tight, so the Giallorossi will need to be able to capitalize on their opportunities to have a realistic shot at winning the three points.
AS Roma Injury & Suspension News
Roma will be missing a key playmaker since Dybala is out with a muscular problem. They will be missing depth in the final third overall since they’ll be without Leon Bailey (thigh) and Edoardo Bove (heart problems).
Lazio vs AS Roma Prediction
Matches between Lazio and AS Roma tend to be intense, tight and with very few goals. Don’t expect that trend to end here. Lazio are unbeaten in their last eight home league derbies against Roma (W4, D4), but regardless of the outcome, this should be another low-scoring affair.
A draw is the most likely result based on how both teams have behaved this season, but exploring another options outside of the results, the under on the mark of 2.5 goals could happen as well. The last seven head-to-head meetings between these two sides have ended with two or fewer total goals scored.
CryptoGamba tip: Under 2.5 total goals – 1.65 @ Stake
Alex Carter
Alex Carter is a crypto gambling expert and senior editor at CryptoGamba with over 5 years of experience reviewing Bitcoin casinos, no-KYC platforms, and decentralized gambling sites. Alex specializes in evaluating withdrawal speeds, bonus fairness, provably fair games, and crypto payment options. Every review on CryptoGamba is personally tested and verified for accuracy, helping players find the safest and most rewarding crypto casinos in 2026.